DCrk

DCrk (Drosophila ortholog of Crk) is the Drosophila melanogaster ortholog of the mammalian proteins Crk and CrkL.^[1]

Crk oncogene
Identifiers
Organism	Drosophila melanogaster
Symbol	Crk
UniProt	Q95RW2
Search for Structures Swiss-model Domains InterPro

Structure and function

DCrk includes one SH2 domain followed by two SH3 domains and interacts with the MyoBlast City (MCB) protein. The DCrk protein is expressed during embryogenesis, declines during the larval stages, and reappears during pupation which suggests that DCrk plays an important role in development.^[1]