DDX31

DEAD (Asp-Glu-Ala-Asp) box polypeptide 31, also known as DDX31, is a human gene.^[5]

DDX31
Identifiers
Aliases	DDX31, PPP1R25, DEAD-box helicase 31
External IDs	OMIM: 616533; MGI: 2682639; HomoloGene: 6389; GeneCards: DDX31; OMA:DDX31 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q34.13 Start 132,592,997 bp[1] End 132,670,401 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 A3 Start 28,730,418 bp[2] End 28,795,583 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad right lobe of thyroid gland left lobe of thyroid gland cerebellar hemisphere right hemisphere of cerebellum skin of leg islet of Langerhans skin of abdomen tibial nerve testicle Top expressed in lumbar spinal ganglion Paneth cell condyle otic vesicle primitive streak fossa medullary collecting duct aortic valve tail of embryo epiblast More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding protein binding hydrolase activity ATP binding helicase activity nucleic acid binding RNA binding Cellular component Golgi apparatus intracellular membrane-bounded organelle nucleus nucleolus cytoplasm Biological process ribosome biogenesis RNA secondary structure unwinding Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64794 227674 Ensembl ENSG00000125485 ENSMUSG00000026806 UniProt Q9H8H2 Q6NZQ2 RefSeq (mRNA) NM_022779 NM_138620 NM_001322340 NM_001322341 NM_001322342 NM_001322343 NM_001322344 NM_001033294 RefSeq (protein) NP_001309269 NP_001309270 NP_001309271 NP_001309272 NP_001309273 NP_073616 NP_619526 NP_001028466 Location (UCSC) Chr 9: 132.59 – 132.67 Mb Chr 2: 28.73 – 28.8 Mb PubMed search [3] [4]
Wikidata
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants.^[5]