DDX43

Probable ATP-dependent RNA helicase DDX43 is an enzyme that in humans is encoded by the DDX43 gene.^[5][6]

DDX43
Identifiers
Aliases	DDX43, CT13, HAGE, DEAD-box helicase 43
External IDs	OMIM: 606286; MGI: 3642857; HomoloGene: 56814; GeneCards: DDX43; OMA:DDX43 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q13 Start 73,394,828 bp[1] End 73,417,566 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 E1 Start 78,303,059 bp[2] End 78,330,869 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte gonad testicle sperm right testis left testis Achilles tendon granulocyte gastric mucosa Top expressed in spermatocyte seminiferous tubule Gonadal ridge spermatid embryo embryo morula zygote blastocyst conjunctival fornix More reference expression data BioGPS More reference expression data
Gene ontology Molecular function ATP binding hydrolase activity nucleotide binding nucleic acid binding helicase activity RNA binding Cellular component intracellular anatomical structure nucleolus cytoplasm Biological process RNA secondary structure unwinding Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55510 100048658 Ensembl ENSG00000080007 ENSMUSG00000070291 UniProt Q9NXZ2 D3Z6P9 RefSeq (mRNA) NM_018665 NM_001191044 RefSeq (protein) NP_061135 NP_001177973 Location (UCSC) Chr 6: 73.39 – 73.42 Mb Chr 9: 78.3 – 78.33 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD box family and displays tumor-specific expression.^[6]