DEC1

Deleted in esophageal cancer 1 is a protein that in humans is encoded by the DEC1 gene.^[3][4][5]

DELEC1
Identifiers
Aliases	DELEC1, CTS9, deleted in esophageal cancer 1, DEC1
External IDs	OMIM: 604767; GeneCards: DELEC1; OMA:DELEC1 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q33.1 Start 114,850,968 bp[1] End 115,402,644 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad granulocyte monocyte Achilles tendon sural nerve popliteal artery tibial arteries smooth muscle tissue stromal cell of endometrium n/a More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 50514 n/a Ensembl ENSG00000173077 n/a UniProt Q9P2X7 n/a RefSeq (mRNA) NM_017418 n/a RefSeq (protein) NP_059114 n/a Location (UCSC) Chr 9: 114.85 – 115.4 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Function

The function of this gene is not known. This gene is located in a region commonly deleted in esophageal squamous cell carcinomas. Gene expression is reduced or absent in these carcinomas, associated with lymph node metastasis, and thus this is a candidate tumor suppressor gene for esophageal squamous cell carcinomas.^[5]