DECR2

Peroxisomal 2,4-dienoyl-CoA reductase is an enzyme that in humans is encoded by the DECR2 gene.^[5][6][7]

DECR2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4FC6, 4FC7
Identifiers
Aliases	DECR2, PDCR, SDR17C1, 2,4-dienoyl-CoA reductase 2, peroxisomal, 2,4-dienoyl-CoA reductase 2
External IDs	OMIM: 615839; MGI: 1347059; HomoloGene: 22223; GeneCards: DECR2; OMA:DECR2 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 401,858 bp[1] End 412,487 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 A3.3|17 13.06 cM Start 26,300,182 bp[2] End 26,309,311 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver right adrenal cortex mucosa of transverse colon left adrenal cortex duodenum renal cortex human kidney muscle of thigh apex of heart body of pancreas Top expressed in interventricular septum left lobe of liver right kidney transitional epithelium of urinary bladder ventromedial nucleus mammillary body proximal tubule seminal vesicula parotid gland lateral geniculate nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function oxidoreductase activity signaling receptor binding 2,4-dienoyl-CoA reductase (NADPH) activity trans-2-enoyl-CoA reductase (NADPH) activity Cellular component peroxisomal membrane peroxisome cytosol Biological process unsaturated fatty acid biosynthetic process fatty acid metabolic process lipid metabolism fatty acid beta-oxidation using acyl-CoA oxidase protein targeting to peroxisome Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26063 26378 Ensembl ENSG00000242612 ENSG00000274296 ENSMUSG00000036775 UniProt Q9NUI1 Q9WV68 RefSeq (mRNA) NM_020664 NM_011933 RefSeq (protein) NP_065715 NP_036063 Location (UCSC) Chr 16: 0.4 – 0.41 Mb Chr 17: 26.3 – 26.31 Mb PubMed search [3] [4]
Wikidata
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