DHRS3

Short-chain dehydrogenase/reductase 3 is an enzyme that in humans is encoded by the DHRS3 gene.^[5][6][7][8]

DHRS3
Identifiers
Aliases	DHRS3, DD83.1, RDH17, Rsdr1, SDR1, SDR16C1, retSDR1, dehydrogenase/reductase (SDR family) member 3, dehydrogenase/reductase 3
External IDs	OMIM: 612830; MGI: 1315215; HomoloGene: 20994; GeneCards: DHRS3; OMA:DHRS3 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.21 Start 12,567,910 bp[1] End 12,618,210 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 E1 Start 144,619,397 bp[2] End 144,654,779 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in olfactory bulb right lobe of liver tibial nerve right lobe of thyroid gland nasal epithelium left lobe of thyroid gland prostate olfactory zone of nasal mucosa seminal vesicula subcutaneous adipose tissue Top expressed in vestibular membrane of cochlear duct transitional epithelium of urinary bladder left lobe of liver right kidney neural layer of retina external carotid artery proximal tubule lobe of prostate epithelium of stomach right lung lobe More reference expression data BioGPS More reference expression data
Gene ontology Molecular function electron transfer activity nucleotide binding oxidoreductase activity NAD-retinol dehydrogenase activity NADP-retinol dehydrogenase activity Cellular component photoreceptor outer segment membrane integral component of membrane endoplasmic reticulum membrane membrane lipid droplet Biological process negative regulation of retinoic acid receptor signaling pathway retinol metabolic process roof of mouth development bone morphogenesis outflow tract morphogenesis regulation of ossification visual perception retinoid metabolic process cardiac septum morphogenesis electron transport chain regulation of retinoic acid receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9249 20148 Ensembl ENSG00000162496 ENSMUSG00000066026 UniProt O75911 Q5SUY4 O88876 RefSeq (mRNA) NM_004753 NM_001319225 NM_001324370 NM_001172424 NM_011303 NM_001357274 NM_001357275 NM_001357276 NM_001357277 RefSeq (protein) NP_001306154 NP_001311299 NP_004744 NP_001165895 NP_035433 NP_001344203 NP_001344204 NP_001344205 NP_001344206 Location (UCSC) Chr 1: 12.57 – 12.62 Mb Chr 4: 144.62 – 144.65 Mb PubMed search [3] [4]
Wikidata
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