DIP2B

DIP2 disco-interacting protein 2 homolog B (Drosophila) is a protein that in humans is encoded by the DIP2B gene.^[5] A member of the disco-interacting protein homolog 2 protein family, it contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1, as well as AMP-binding sites. The presence of these sites suggests that DIP2B may participate in DNA methylation. This gene is located near a folate-sensitive fragile site.^[5][6]

DIP2B
Identifiers
Aliases	DIP2B, disco interacting protein 2 homolog B
External IDs	OMIM: 611379; MGI: 2145977; HomoloGene: 72227; GeneCards: DIP2B; OMA:DIP2B - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.12 Start 50,504,985 bp[1] End 50,748,657 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 F1 Start 99,936,545 bp[2] End 100,117,354 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in inferior ganglion of vagus nerve cerebellar vermis subthalamic nucleus corpus callosum medulla oblongata superior vestibular nucleus skin of arm pars reticulata pons external globus pallidus Top expressed in vestibular membrane of cochlear duct primary oocyte secondary oocyte blood perirhinal cortex sciatic nerve conjunctival fornix spermatid entorhinal cortex cingulate gyrus More reference expression data BioGPS n/a
Gene ontology Molecular function catalytic activity molecular function Cellular component cytoplasm extracellular exosome membrane nucleus Biological process metabolism biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57609 239667 Ensembl ENSG00000066084 ENSMUSG00000023026 UniProt Q9P265 Q3UH60 RefSeq (mRNA) NM_020849 NM_173602 NM_001159361 NM_172819 RefSeq (protein) NP_775873 NP_001152833 NP_766407 NP_001389830 Location (UCSC) Chr 12: 50.5 – 50.75 Mb Chr 15: 99.94 – 100.12 Mb PubMed search [3] [4]
Wikidata
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