DLEU1

In molecular biology, deleted in lymphocytic leukemia 1 (non-protein coding), also known as DLEU1, is a long non-coding RNA. In humans it is located on chromosome 13q14. The DLEU1 gene was originally identified as a potential tumour suppressor gene and is often deleted in patients with B-cell chronic lymphocytic leukemia.^[3] It was later discovered to be a long non-coding RNA with over 20 different splice variants.^[4]

DLEU1
Identifiers
Aliases	DLEU1, BCMS, BCMS1, DLB1, DLEU2, LEU1, LEU2, LINC00021, NCRNA00021, XTP6, deleted in lymphocytic leukemia 1 (non-protein coding), deleted in lymphocytic leukemia 1
External IDs	OMIM: 605765; GeneCards: DLEU1; OMA:DLEU1 - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q14.2-q14.3 Start 50,082,169 bp[1] End 50,906,856 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad testicle islet of Langerhans sural nerve epithelium of colon ventricular zone Achilles tendon monocyte bone marrow cells muscle of thigh n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 10301 n/a Ensembl ENSG00000176124 n/a UniProt n a n/a RefSeq (mRNA) NM_005887 n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 13: 50.08 – 50.91 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

See also

• Long noncoding RNA