DLST

Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial is an enzyme that in humans is encoded by the DLST gene.^[5][6]

DLST
Identifiers
Aliases	DLST, DLTS, dihydrolipoamide S-succinyltransferase, PGL7, KGD2
External IDs	OMIM: 126063; MGI: 1926170; HomoloGene: 1456; GeneCards: DLST; OMA:DLST - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q24.3 Start 74,881,891 bp[1] End 74,903,743 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 D1 Start 85,157,607 bp[2] End 85,181,619 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart right adrenal cortex left ventricle gastrocnemius muscle left adrenal gland left adrenal cortex right auricle of heart secondary oocyte muscle of thigh skin of leg Top expressed in right ventricle muscle of thigh digastric muscle myocardium of ventricle thoracic diaphragm brown adipose tissue right kidney soleus muscle cardiac muscles sternocleidomastoid muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity dihydrolipoyllysine-residue succinyltransferase activity acyltransferase activity protein binding Cellular component oxoglutarate dehydrogenase complex membrane myelin sheath mitochondrial matrix mitochondrion extracellular exosome nucleus Biological process tricarboxylic acid cycle lysine catabolic process generation of precursor metabolites and energy L-lysine catabolic process to acetyl-CoA via saccharopine metabolism cellular nitrogen compound metabolic process 2-oxoglutarate metabolic process succinyl-CoA metabolic process histone succinylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1743 78920 Ensembl ENSG00000119689 ENSMUSG00000004789 UniProt P36957 Q9D2G2 RefSeq (mRNA) NM_001244883 NM_001933 NM_030225 RefSeq (protein) NP_001231812 NP_001924 NP_084501 Location (UCSC) Chr 14: 74.88 – 74.9 Mb Chr 12: 85.16 – 85.18 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles. ^{[§ 1]}

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|alt=TCACycle_WP78 edit]]

TCACycle_WP78 edit

1. The interactive pathway map can be edited at WikiPathways: "TCACycle_WP78".