DNAJC1

DnaJ homolog subfamily C member 1 is a protein that in humans is encoded by the DNAJC1 gene.^[5]

DNAJC1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CQQ, 2CQR
Identifiers
Aliases	DNAJC1, DNAJL1, ERdj1, HTJ1, MTJ1, DnaJ heat shock protein family (Hsp40) member C1
External IDs	OMIM: 611207; MGI: 103268; HomoloGene: 7293; GeneCards: DNAJC1; OMA:DNAJC1 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10p12.31 Start 21,756,548 bp[1] End 22,003,769 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 A3 Start 18,200,465 bp[2] End 18,397,641 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte pylorus cardia parotid gland lower lobe of lung lactiferous duct pericardium renal medulla mucosa of paranasal sinus tibia Top expressed in lacrimal gland parotid gland seminal vesicula external carotid artery internal carotid artery prostate lobe of prostate Rostral migratory stream body of femur decidua More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding ATPase activator activity chaperone binding protein binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component integral component of membrane organelle membrane plasma membrane nuclear membrane endoplasmic reticulum membrane endoplasmic reticulum membrane nucleus intracellular membrane-bounded organelle Biological process negative regulation of proteolysis protein folding regulation of translation regulation of protein secretion positive regulation of ATP-dependent activity regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64215 13418 Ensembl ENSG00000136770 ENSMUSG00000026740 UniProt Q96KC8 Q61712 RefSeq (mRNA) NM_022365 NM_001190817 NM_007869 RefSeq (protein) NP_071760 NP_001177746 NP_031895 Location (UCSC) Chr 10: 21.76 – 22 Mb Chr 2: 18.2 – 18.4 Mb PubMed search [3] [4]
Wikidata
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Interactions

DNAJC1 has been shown to interact with Alpha 1-antichymotrypsin.^[6]