DNASE1L2

Deoxyribonuclease-1-like 2 is an enzyme that in humans is encoded by the DNASE1L2 gene.^[5][6][7]

DNASE1L2
Identifiers
Aliases	DNASE1L2, DNAS1L2, deoxyribonuclease I-like 2, deoxyribonuclease 1 like 2
External IDs	OMIM: 602622; MGI: 1913955; HomoloGene: 74391; GeneCards: DNASE1L2; OMA:DNASE1L2 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 2,235,816 bp[1] End 2,238,711 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 24,659,055 bp[2] End 24,662,079 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen skin of leg skin of arm right hemisphere of cerebellum right lobe of thyroid gland left lobe of thyroid gland right frontal lobe skin of thigh vulva Brodmann area 9 Top expressed in lip esophagus transitional epithelium of urinary bladder skin of back skin of external ear umbilical cord neural layer of retina hair follicle granulocyte skin of abdomen More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding calcium ion binding endonuclease activity nuclease activity hydrolase activity deoxyribonuclease activity metal ion binding deoxyribonuclease I activity Cellular component cytoplasm extracellular region nucleus Biological process hair follicle development DNA metabolic process DNA catabolic process corneocyte development nucleic acid phosphodiester bond hydrolysis DNA catabolic process, endonucleolytic Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1775 66705 Ensembl ENSG00000167968 ENSMUSG00000024136 UniProt Q92874 Q9D1G0 RefSeq (mRNA) NM_001301680 NM_001374 NM_025718 RefSeq (protein) NP_001288609 NP_001365 NP_079994 Location (UCSC) Chr 16: 2.24 – 2.24 Mb Chr 17: 24.66 – 24.66 Mb PubMed search [3] [4]
Wikidata
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