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DPY19L2
Protein-coding gene in humans From Wikipedia, the free encyclopedia
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Dpy-19-like 2 (C. elegans) is a protein that in humans is encoded by the DPY19L2 gene.[5]
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Function
The C. elegans gene dpy-19 belongs to the dpy ("dumpy" phenotype)[6] gene class and encodes DPY-19, transmembrane protein with C-linked mannosyltransferase activity.[7][8] In humans, it is highly expressed in testis, and is required for sperm head elongation and acrosome formation during spermatogenesis. Mutations in this gene are associated with an infertility disorder, spermatogenic failure type 9 (SPGF9).
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References
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