DTYMK

Thymidylate kinase also known as deoxythymidylate kinase or dTMP kinase is an enzyme that in humans is encoded by the DTYMK gene.^[5][6][7] and belongs to thymidylate kinase family of proteins.

DTYMK
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1E9F, 1E9E, 1NMY, 1E2G, 1E9D, 1E98, 1E2E, 1NN0, 1E2Q, 1E9C, 1E2F, 1NN5, 1E99, 2XX3, 1NMZ, 1E9A, 1E2D, 1E9B, 1NMX, 1NN1, 1NN3
Identifiers
Aliases	DTYMK, CDC8, PP3731, TMPK, TYMK, deoxythymidylate kinase, CONPM
External IDs	OMIM: 188345; MGI: 108396; HomoloGene: 6285; GeneCards: DTYMK; OMA:DTYMK - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q37.3 Start 241,675,747 bp[1] End 241,686,944 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 D|1 47.34 cM Start 93,720,298 bp[2] End 93,729,656 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone gonad mucosa of transverse colon ganglionic eminence stromal cell of endometrium right adrenal gland apex of heart granulocyte right adrenal cortex right hemisphere of cerebellum Top expressed in endocardial cushion renal corpuscle primitive streak medullary collecting duct Paneth cell ureter embryo ventricular zone condyle embryo More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity nucleotide binding uridylate kinase activity kinase activity thymidylate kinase activity nucleoside monophosphate kinase activity ATP binding nucleoside diphosphate kinase activity Cellular component mitochondrial intermembrane space mitochondrial matrix cytoplasm mitochondrion cytosol nucleus Biological process nucleobase-containing small molecule interconversion nucleotide biosynthetic process response to cadmium ion phosphorylation cellular response to growth factor stimulus dTTP biosynthetic process response to estrogen dTDP biosynthetic process dUDP biosynthetic process myoblast differentiation cell population proliferation nucleoside monophosphate phosphorylation nucleotide phosphorylation nucleoside diphosphate phosphorylation thymidine biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1841 21915 Ensembl ENSG00000168393 ENSMUSG00000026281 UniProt P23919 P97930 RefSeq (mRNA) NM_001165031 NM_012145 NM_001320902 NM_001320903 NM_001320904 NM_001320905 NM_001105667 NM_023136 RefSeq (protein) NP_001158503 NP_001307831 NP_001307832 NP_001307833 NP_001307834 NP_036277 NP_001099137 NP_075625 Location (UCSC) Chr 2: 241.68 – 241.69 Mb Chr 1: 93.72 – 93.73 Mb PubMed search [3] [4]
Wikidata
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