DUSP18

Dual specificity protein phosphatase 18 is an enzyme that is encoded by the DUSP18 gene in humans.^[5][6]

DUSP18
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2ESB
Identifiers
Aliases	DUSP18, DSP18, DUSP20, LMWDSP20, bK963H5.1, dual specificity phosphatase 18
External IDs	OMIM: 611446; MGI: 1922469; HomoloGene: 34984; GeneCards: DUSP18; OMA:DUSP18 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q12.2 Start 30,652,051 bp[1] End 30,667,887 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 A1 Start 3,845,240 bp[2] End 3,851,296 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte bronchial epithelial cell mucosa of ileum left testis right testis testicle mucosa of paranasal sinus sperm right uterine tube blood Top expressed in zygote interventricular septum secondary oocyte myocardium of ventricle Rostral migratory stream dentate gyrus of hippocampal formation granule cell lip islet of Langerhans soleus muscle muscle of thigh More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein tyrosine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity phosphoprotein phosphatase activity hydrolase activity phosphatase activity protein tyrosine/serine/threonine phosphatase activity Cellular component cytoplasm nucleus nucleoplasm mitochondrion membrane mitochondrial inner membrane Biological process protein dephosphorylation peptidyl-tyrosine dephosphorylation peptidyl-threonine dephosphorylation dephosphorylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 150290 75219 Ensembl ENSG00000167065 ENSMUSG00000047205 UniProt Q8NEJ0 Q8VE01 RefSeq (mRNA) NM_001304794 NM_001304795 NM_001304796 NM_152511 NM_173745 RefSeq (protein) NP_001291723 NP_001291724 NP_001291725 NP_689724 NP_776106 Location (UCSC) Chr 22: 30.65 – 30.67 Mb Chr 11: 3.85 – 3.85 Mb PubMed search [3] [4]
Wikidata
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