DYNC1I2

Cytoplasmic dynein 1 intermediate chain 2 is a protein that in humans is encoded by the DYNC1I2 gene.^[5][6][7]

DYNC1I2
Identifiers
Aliases	DYNC1I2, DNCI2, IC2, DIC74, dynein cytoplasmic 1 intermediate chain 2, NEDMIBA
External IDs	OMIM: 603331; MGI: 107750; HomoloGene: 133934; GeneCards: DYNC1I2; OMA:DYNC1I2 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q31.1 Start 171,687,409 bp[1] End 171,750,158 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 C2|2 42.38 cM Start 71,042,050 bp[2] End 71,093,647 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon ganglionic eminence C1 segment ventricular zone sural nerve smooth muscle tissue islet of Langerhans popliteal artery tibial arteries Descending thoracic aorta Top expressed in genital tubercle ganglionic eminence spermatocyte barrel cortex medial ganglionic eminence fossa superior cervical ganglion condyle median eminence zygote More reference expression data BioGPS More reference expression data
Gene ontology Molecular function microtubule motor activity protein binding cytoskeletal motor activity plus-end-directed microtubule motor activity dynein light chain binding dynein heavy chain binding Cellular component vesicle cytosol centrosome dynein complex cytoskeleton cytoplasm microtubule cytoplasmic dynein complex Biological process antigen processing and presentation of exogenous peptide antigen via MHC class II endoplasmic reticulum to Golgi vesicle-mediated transport G2/M transition of mitotic cell cycle viral process microtubule-based movement ciliary basal body-plasma membrane docking transport along microtubule regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1781 13427 Ensembl ENSG00000077380 ENSMUSG00000027012 UniProt Q13409 O88487 RefSeq (mRNA) NM_001271785 NM_001271786 NM_001271787 NM_001271788 NM_001271789 NM_001271790 NM_001378 NM_001320882 NM_001320883 NM_001320884 NM_001378455 NM_001378456 NM_001198872 NM_001198873 NM_001198874 NM_001198875 NM_001198876 NM_001198877 NM_001198878 NM_010064 NM_001347173 RefSeq (protein) NP_001258714 NP_001258715 NP_001258716 NP_001258717 NP_001258718 NP_001258719 NP_001307811 NP_001307812 NP_001307813 NP_001369 NP_001365384 NP_001365385 NP_001185801 NP_001185802 NP_001185803 NP_001185804 NP_001185805 NP_001185806 NP_001185807 NP_001334102 NP_034194 Location (UCSC) Chr 2: 171.69 – 171.75 Mb Chr 2: 71.04 – 71.09 Mb PubMed search [3] [4]
Wikidata
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