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Deltapapillomavirus

Genus of viruses From Wikipedia, the free encyclopedia

Deltapapillomavirus
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Deltapapillomavirus is a genus of viruses in the family Papillomaviridae.[1] Ruminants serve as natural hosts. There are seven species in this genus. Diseases associated with this genus include: warts (papillomas and fibropapillomas) of the skin and alimentary tract (rarely cancers of the alimentary tract and urinary bladder); possibly responsible for the skin tumour equine sarcoid in horses and donkeys.[2][3]

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Taxonomy

The following seven species are assigned to the genus:[3]

  • Deltapapillomavirus 1
  • Deltapapillomavirus 2
  • Deltapapillomavirus 3
  • Deltapapillomavirus 4
  • Deltapapillomavirus 5
  • Deltapapillomavirus 6
  • Deltapapillomavirus 7

Structure

Viruses in Deltapapillomavirus are non-enveloped, with icosahedral geometries. The diameter is around 60 nm. Genomes are circular, around 8kb in length.[2]

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Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Ruminants serve as the natural host. Transmission routes are contact.[2]

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References

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