Derlin-3

Derlin-3 is a protein that in humans is encoded by the DERL3 gene.^[5][6]

DERL3
Identifiers
Aliases	DERL3, C22orf14, IZP6, LLN2, derlin-3, derlin 3
External IDs	OMIM: 610305; MGI: 1917627; HomoloGene: 41566; GeneCards: DERL3; OMA:DERL3 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q11.23 Start 23,834,503 bp[1] End 23,839,128 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 C1 Start 75,893,413 bp[2] End 75,895,941 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bone marrow cells duodenum tonsil epithelium of colon appendix body of pancreas lymph node spleen mucosa of transverse colon rectum Top expressed in salivary gland submandibular gland lacrimal gland parotid gland zygote seminal vesicula primary oocyte secondary oocyte pyloric antrum epithelium of stomach More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component integral component of membrane integral component of endoplasmic reticulum membrane endoplasmic reticulum endoplasmic reticulum membrane membrane signal recognition particle receptor complex signal recognition particle Biological process endoplasmic reticulum unfolded protein response negative regulation of retrograde protein transport, ER to cytosol protein N-linked glycosylation via asparagine ubiquitin-dependent ERAD pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 91319 70377 Ensembl ENSG00000274437 ENSG00000099958 ENSMUSG00000009092 UniProt Q96Q80 Q9D8K3 RefSeq (mRNA) NM_001002862 NM_001135751 NM_198440 NM_001363072 NM_024440 RefSeq (protein) NP_001002862 NP_001129223 NP_940842 NP_001350001 NP_077760 NP_001345912 NP_001345913 NP_001345914 Location (UCSC) Chr 22: 23.83 – 23.84 Mb Chr 10: 75.89 – 75.9 Mb PubMed search [3] [4]
Wikidata
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See also

• Derlin-1
• Derlin-2