Difludiazepam

Difludiazepam
Legal status
Legal status	CA: Schedule IV; DE: NpSG (Industrial and scientific use only); UK: Under Psychoactive Substances Act;
Identifiers
	IUPAC name 7-chloro-5-(2,6-difluorophenyl)-1-methyl-1H-benzo[e] [1,4]diazepin-2(3H)-one;
CAS Number	39080-67-6 ;
PubChem CID	44366236;
ChemSpider	23222150;
UNII	7N3B9XEC7B;
ChEMBL	ChEMBL346673;
CompTox Dashboard (EPA)	DTXSID001135292 ;
Chemical and physical data
Formula	C16H11ClF2N2O
Molar mass	320.72 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Fc3cccc(F)c3C2=NCC(=O)N(C)c1ccc(Cl)cc12;
	InChI InChI=1S/C16H11ClF2N2O/c1-21-13-6-5-9(17)7-10(13)16(20-8-14(21)22)15-11(18)3-2-4-12(15)19/h2-7H,8H2,1H3; Key:DUNFPASORLTEGN-UHFFFAOYSA-N;

Difludiazepam^[1] (Ro07-4065) is a benzodiazepine derivative which is the 2',6'-difluoro derivative of fludiazepam. It was invented in the 1970s but was never marketed, and has been used as a research tool to help determine the shape and function of the GABA_A receptors, at which it has an IC₅₀ of 4.1nM.^[2]^[3]^[4] Difludiazepam has subsequently been sold as a designer drug, and was first notified to the EMCDDA by Swedish authorities in 2017.^[5]^[6]

Quick facts Legal status, Identifiers ...

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Difludiazepam

See also

References

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