E2F7

Transcription factor E2F7 is a protein that in humans is encoded by the E2F7 gene.^[5][6]

E2F7
Identifiers
Aliases	E2F7, E2F transcription factor 7
External IDs	OMIM: 612046; MGI: 1289147; HomoloGene: 18685; GeneCards: E2F7; OMA:E2F7 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q21.2 Start 77,021,248 bp[1] End 77,065,569 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 D1|10 57.74 cM Start 110,581,300 bp[2] End 110,623,245 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone thymus gonad ganglionic eminence testicle secondary oocyte stromal cell of endometrium mucosa of ileum bone marrow cells pancreatic ductal cell Top expressed in otic vesicle hand primitive streak fossa tail of embryo condyle yolk sac genital tubercle abdominal wall mandibular prominence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription corepressor activity protein binding DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific transcription factor binding sequence-specific DNA binding Cellular component transcription regulator complex nucleus nucleoplasm nuclear speck RNA polymerase II transcription regulator complex Biological process trophoblast giant cell differentiation regulation of transcription, DNA-templated chorionic trophoblast cell differentiation negative regulation of transcription involved in G1/S transition of mitotic cell cycle placenta development DNA damage response, signal transduction by p53 class mediator hepatocyte differentiation negative regulation of transcription by RNA polymerase II transcription, DNA-templated cellular response to DNA damage stimulus negative regulation of G1/S transition of mitotic cell cycle cell cycle negative regulation of cytokinesis positive regulation of DNA endoreduplication positive regulation of transcription by RNA polymerase II sprouting angiogenesis DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest negative regulation of cell population proliferation regulation of cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 144455 52679 Ensembl ENSG00000165891 ENSMUSG00000020185 UniProt Q96AV8 Q6S7F2 RefSeq (mRNA) NM_203394 NM_178609 NM_001358560 RefSeq (protein) NP_976328 NP_848724 NP_001345489 Location (UCSC) Chr 12: 77.02 – 77.07 Mb Chr 10: 110.58 – 110.62 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse