E74 like ets transcription factor 3

E74 like ETS transcription factor 3 is a protein that in humans is encoded by the ELF3 gene. ^[5]

ELF3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2E8P
Identifiers
Aliases	ELF3, EPR-1, ERT, ESE-1, ESX, E74 like ETS transcription factor 3
External IDs	OMIM: 602191; MGI: 1101781; HomoloGene: 3265; GeneCards: ELF3; OMA:ELF3 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 202,007,945 bp[1] End 202,017,183 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E4 Start 135,181,313 bp[2] End 135,186,306 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in olfactory zone of nasal mucosa mucosa of transverse colon rectum pancreatic ductal cell gallbladder body of pancreas minor salivary glands islet of Langerhans right uterine tube palpebral conjunctiva Top expressed in corneal stroma pyloric antrum epithelium of stomach mucous cell of stomach blastocyst duodenum colon left colon medulla of thymus crypt of lieberkuhn of small intestine More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding sequence-specific DNA binding DNA-binding transcription factor activity transcription coactivator activity DNA-binding transcription activator activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding protein binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasm nucleus Golgi apparatus cytosol nucleoplasm Biological process cell differentiation regulation of transcription, DNA-templated epithelial cell differentiation regulation of transcription by RNA polymerase II anatomical structure morphogenesis extracellular matrix organization transcription by RNA polymerase II transcription, DNA-templated multicellular organism development positive regulation of transcription, DNA-templated epidermis development inflammatory response negative regulation of transcription, DNA-templated blastocyst development positive regulation of transcription by RNA polymerase II mammary gland involution positive regulation of Notch signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1999 13710 Ensembl ENSG00000163435 ENSMUSG00000003051 UniProt P78545 Q3UPW2 RefSeq (mRNA) NM_001114309 NM_004433 NM_001163131 NM_007921 RefSeq (protein) NP_001107781 NP_004424 NP_001156603 NP_031947 Location (UCSC) Chr 1: 202.01 – 202.02 Mb Chr 1: 135.18 – 135.19 Mb PubMed search [3] [4]
Wikidata
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