EGF module-containing mucin-like hormone receptor

The EGF module-containing Mucin-like hormone Receptors (EMRs) are closely related subgroup of G protein-coupled receptors (GPCRs). These receptors have a unique hybrid structure in which an extracellular epidermal growth factor (EGF)-like domain is fused to a GPCR domain through a mucin-like stalk.^[1][2][3][4] There are four variants of EMR labeled 1–4, each encoded by a separate gene. These receptors are predominantly expressed in cells of the immune system and bind ligands such as CD55.^[5]

egf-like module containing, mucin-like, hormone receptor-like 1
Identifiers
Symbol	EMR1
Alt. symbols	TM7LN3
IUPHAR	182
NCBI gene	2015
HGNC	3336
OMIM	600493
RefSeq	NM_001974
UniProt	Q14246
Other data
Locus	Chr. 19 p13.3
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egf-like module containing, mucin-like, hormone receptor-like 2
Identifiers
Symbol	EMR2
IUPHAR	183
NCBI gene	30817
HGNC	3337
OMIM	606100
RefSeq	NM_152916
UniProt	Q9UHX3
Other data
Locus	Chr. 19 p13.1
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egf-like module containing, mucin-like, hormone receptor-like 3
Identifiers
Symbol	EMR3
IUPHAR	184
NCBI gene	84658
HGNC	23647
OMIM	606101
RefSeq	NM_032571
UniProt	Q9BY15
Other data
Locus	Chr. 19 p13.1
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egf-like module containing, mucin-like, hormone receptor-like 4 pseudogene
Identifiers
Symbol	EMR4P
Alt. symbols	GPR127
NCBI gene	326342
HGNC	19240
RefSeq	XM_940358
UniProt	Q86SQ3
Other data
Locus	Chr. 19 p13.3
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