EIF4A2

Eukaryotic initiation factor 4A-II is a protein that in humans is encoded by the EIF4A2 gene.^[5][6]

EIF4A2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3BOR
Identifiers
Aliases	EIF4A2, BM-010, DDX2B, EIF4A, EIF4F, eIF-4A-II, eIF4A-II, eukaryotic translation initiation factor 4A2
External IDs	OMIM: 601102; MGI: 106906; HomoloGene: 1487; GeneCards: EIF4A2; OMA:EIF4A2 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q27.3 Start 186,783,205 bp[1] End 186,789,897 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16 B1|16 13.93 cM Start 22,926,194 bp[2] End 22,932,886 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte endothelial cell cerebellar vermis germinal epithelium postcentral gyrus superior frontal gyrus lateral nuclear group of thalamus Region I of hippocampus proper Brodmann area 23 primary visual cortex Top expressed in dentate gyrus of hippocampal formation granule cell diencephalon Hypothalamus hippocampus proper cerebellar cortex primary visual cortex superior frontal gyrus olfactory bulb uterus ovary More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding translation initiation factor activity helicase activity protein binding nucleic acid binding hydrolase activity ATP binding ATPase activity RNA binding Cellular component cytosol perinuclear region of cytoplasm eukaryotic translation initiation factor 4F complex nucleolus Biological process nuclear-transcribed mRNA poly(A) tail shortening RNA secondary structure unwinding viral process negative regulation of RNA-directed 5'-3' RNA polymerase activity protein biosynthesis regulation of translational initiation translational initiation cellular response to leukemia inhibitory factor Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1974 13682 Ensembl ENSG00000156976 ENSMUSG00000022884 UniProt Q14240 P10630 RefSeq (mRNA) NM_001967 NM_001123037 NM_001123038 NM_013506 NM_001347179 RefSeq (protein) NP_001958 NP_001116509 NP_001116510 NP_001334108 NP_038534 Location (UCSC) Chr 3: 186.78 – 186.79 Mb Chr 16: 22.93 – 22.93 Mb PubMed search [3] [4]
Wikidata
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