ELF2

E74-like factor 2 (ELF2), formerly known as new Ets-related factor (NERF), is an ETS family transcription factor.^[5] In humans this protein is encoded by the ELF2 gene.^[6]

ELF2
Identifiers
Aliases	ELF2, EU32, NERF, NERF-1A, NERF-1B, NERF-1a,b, NERF-2, E74 like ETS transcription factor 2
External IDs	MGI: 1916507; HomoloGene: 5006; GeneCards: ELF2; OMA:ELF2 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q31.1 Start 139,028,112 bp[1] End 139,177,218 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 C Start 51,160,141 bp[2] End 51,248,084 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon epithelium of colon ganglionic eminence ventricular zone muscle of thigh Descending thoracic aorta right lung skin of thigh skin of hip ascending aorta Top expressed in spermatocyte spermatid seminiferous tubule ventricular zone zygote ganglionic eminence dermis Rostral migratory stream tail of embryo thymus More reference expression data BioGPS n/a
Gene ontology Molecular function DNA-binding transcription factor activity sequence-specific DNA binding DNA binding protein binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus cytosol nuclear body nucleoplasm Biological process regulation of transcription by RNA polymerase II positive regulation of transcription, DNA-templated cell differentiation negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription, DNA-templated regulation of B cell receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1998 69257 Ensembl ENSG00000109381 ENSMUSG00000037174 UniProt Q15723 Q9JHC9 RefSeq (mRNA) NM_001276457 NM_001276458 NM_001276459 NM_006874 NM_201999 NM_001331036 NM_001291059 NM_001291062 NM_001291063 NM_023502 NM_001356358 RefSeq (protein) NP_001263386 NP_001263387 NP_001263388 NP_001317965 NP_006865 NP_973728 NP_001358253 NP_001358265 NP_001358266 NP_001358267 NP_001358268 NP_001277988 NP_001277991 NP_001277992 NP_075991 NP_001343287 Location (UCSC) Chr 4: 139.03 – 139.18 Mb Chr 3: 51.16 – 51.25 Mb PubMed search [3] [4]
Wikidata
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