EMCN

Endomucin is a protein that in humans is encoded by the EMCN gene.^[5][6][7] Endomucin is a marker for endothelial cells^[8] and hematopoietic stem cells.^[9]

EMCN
Identifiers
Aliases	EMCN, EMCN2, MUC14, endomucin
External IDs	OMIM: 608350; MGI: 1891716; HomoloGene: 9438; GeneCards: EMCN; OMA:EMCN - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q24 Start 100,395,341 bp[1] End 100,880,126 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 G3 Start 137,046,828 bp[2] End 137,137,946 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon lower lobe of lung parietal pleura skin of hip renal medulla right lobe of thyroid gland visceral pleura human kidney right lung gallbladder Top expressed in left lung lobe adrenal gland genital tubercle atrioventricular valve right kidney atrium cardiac muscle tissue of left ventricle interventricular septum right lung human kidney More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 51705 59308 Ensembl ENSG00000164035 ENSMUSG00000054690 UniProt Q9ULC0 Q9R0H2 RefSeq (mRNA) NM_001159694 NM_016242 NM_001163522 NM_016885 RefSeq (protein) NP_001153166 NP_057326 NP_001156994 NP_058581 Location (UCSC) Chr 4: 100.4 – 100.88 Mb Chr 3: 137.05 – 137.14 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Function

EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.^[5][7]