Band 4.1-like protein 3

Band 4.1-like protein 3 is a protein that in humans is encoded by the EPB41L3 gene.^[5][6][7]

EPB41L3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2HE7, 3BIN
Identifiers
Aliases	EPB41L3, 4.1B, DAL-1, DAL1, erythrocyte membrane protein band 4.1 like 3
External IDs	OMIM: 605331; MGI: 103008; HomoloGene: 49308; GeneCards: EPB41L3; OMA:EPB41L3 - orthologs
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18p11.31 Start 5,392,381 bp[1] End 5,630,700 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 E1.3|17 40.15 cM Start 69,075,683 bp[2] End 69,289,989 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pons lateral nuclear group of thalamus Brodmann area 10 C1 segment sperm frontal pole middle frontal gyrus spinal ganglia subthalamic nucleus paraflocculus of cerebellum Top expressed in facial motor nucleus anterior horn of spinal cord epithelium of small intestine central gray substance of midbrain pontine nuclei deep cerebellar nuclei medial vestibular nucleus lateral geniculate nucleus inferior colliculi superior colliculus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity cytoskeletal protein binding structural constituent of cytoskeleton protein binding actin binding Cellular component cytoplasm membrane cell junction juxtaparanode region of axon paranode region of axon axolemma cell-cell junction cytosol cytoskeleton plasma membrane postsynaptic density Biological process apoptotic process cortical cytoskeleton organization cytoskeleton organization regulation of cell growth cortical actin cytoskeleton organization paranodal junction assembly myelin maintenance protein localization to juxtaparanode region of axon neuron projection morphogenesis protein localization to plasma membrane regulation of cell shape protein localization to paranode region of axon actomyosin structure organization biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23136 13823 Ensembl ENSG00000082397 ENSMUSG00000024044 UniProt Q9Y2J2 Q9WV92 RefSeq (mRNA) NM_001281533 NM_001281534 NM_001281535 NM_012307 NM_001330557 NM_013813 NM_001355732 NM_001355733 NM_001355734 NM_001355735 NM_001355736 RefSeq (protein) NP_001268462 NP_001268463 NP_001268464 NP_001317486 NP_036439 NP_038841 NP_001342661 NP_001342662 NP_001342663 NP_001342664 NP_001342665 Location (UCSC) Chr 18: 5.39 – 5.63 Mb Chr 17: 69.08 – 69.29 Mb PubMed search [3] [4]
Wikidata
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Interactions

EPB41L3 has been shown to interact with YWHAB,^[8][9] YWHAH,^[9] YWHAG^[8][9] and Cell adhesion molecule 1.^[10]