EPC1

Enhancer of polycomb homolog 1 is a protein that in humans is encoded by the EPC1 gene.^[5][6]

EPC1
Identifiers
Aliases	EPC1, Epl1, enhancer of polycomb homolog 1
External IDs	OMIM: 610999; MGI: 1278322; HomoloGene: 32627; GeneCards: EPC1; OMA:EPC1 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10p11.22 Start 32,267,751 bp[1] End 32,378,798 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 A1 Start 6,435,951 bp[2] End 6,516,108 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in epithelium of colon bone marrow cells secondary oocyte pancreatic epithelial cell mucosa of ileum endothelial cell trabecular bone tibialis anterior muscle epithelium of lactiferous gland lactiferous duct Top expressed in Rostral migratory stream primary oocyte renal corpuscle medullary collecting duct cumulus cell fossa zygote conjunctival fornix condyle external carotid artery More reference expression data BioGPS n/a
Gene ontology Molecular function histone acetyltransferase activity protein binding Cellular component Piccolo NuA4 histone acetyltransferase complex nuclear membrane nucleus NuA4 histone acetyltransferase complex nucleoplasm Biological process vascular associated smooth muscle cell differentiation regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II histone H4 acetylation positive regulation of transcription by RNA polymerase II histone H2A acetylation regulation of transcription by RNA polymerase II positive regulation of transcription, DNA-templated transcription, DNA-templated regulation of growth negative regulation of gene expression, epigenetic negative regulation of transcription, DNA-templated negative regulation of G0 to G1 transition chromatin organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 80314 13831 Ensembl ENSG00000120616 ENSMUSG00000024240 UniProt Q9H2F5 Q8C9X6 RefSeq (mRNA) NM_001272004 NM_001272019 NM_001282391 NM_025209 NM_001276350 NM_007935 NM_027497 RefSeq (protein) NP_001258933 NP_001258948 NP_001269320 NP_079485 NP_001263279 NP_031961 NP_081773 Location (UCSC) Chr 10: 32.27 – 32.38 Mb Chr 18: 6.44 – 6.52 Mb PubMed search [3] [4]
Wikidata
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