EPS15L1

Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1 gene.^[5]

EPS15L1
Identifiers
Aliases	EPS15L1, EPS15R, epidermal growth factor receptor pathway substrate 15 like 1
External IDs	OMIM: 616826; MGI: 104582; HomoloGene: 31881; GeneCards: EPS15L1; OMA:EPS15L1 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.11 Start 16,355,239 bp[1] End 16,472,085 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 B3.3 Start 73,094,843 bp[2] End 73,175,304 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle apex of heart muscle of thigh right auricle of heart right hemisphere of cerebellum left ventricle sural nerve anterior pituitary right frontal lobe skin of leg Top expressed in genital tubercle tail of embryo zygote ventricular zone neural layer of retina granulocyte Rostral migratory stream lip primary oocyte superior frontal gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding protein binding metal ion binding cadherin binding Cellular component clathrin coat of coated pit plasma membrane clathrin-coated pit membrane nucleus cytosol Biological process negative regulation of epidermal growth factor receptor signaling pathway endocytosis membrane organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 58513 13859 Ensembl ENSG00000127527 ENSMUSG00000006276 UniProt Q9UBC2 Q60902 RefSeq (mRNA) NM_001258374 NM_001258375 NM_001258376 NM_021235 NM_001122832 NM_001289859 NM_007944 RefSeq (protein) NP_001245303 NP_001245304 NP_001245305 NP_067058 NP_001245304.1 NP_001116304 NP_001276788 NP_031970 Location (UCSC) Chr 19: 16.36 – 16.47 Mb Chr 8: 73.09 – 73.18 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

EPS15L1 has been shown to interact with HRB.^[6]