ERO1L

ERO1-like protein alpha is a protein that in humans is encoded by the ERO1L gene.^[5][6]

ERO1A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3AHQ, 3AHR
Identifiers
Aliases	ERO1A, ERO1-alpha, ERO1LA, ERO1-L, ERO1-L-alpha, ERO1L, Ero1alpha, endoplasmic reticulum oxidoreductase alpha, endoplasmic reticulum oxidoreductase 1 alpha
External IDs	OMIM: 615435; MGI: 1354385; HomoloGene: 49392; GeneCards: ERO1A; OMA:ERO1A - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q22.1 Start 52,639,915 bp[1] End 52,695,900 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 C1 Start 45,520,544 bp[2] End 45,556,228 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oral cavity buccal mucosa cell mucosa of pharynx body of tongue pericardium tonsil gums amniotic fluid islet of Langerhans vena cava Top expressed in cumulus cell epithelium of stomach pyloric antrum mucous cell of stomach decidua gastrula granulocyte hair follicle epithelium of small intestine tail of embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor protein binding oxidoreductase activity protein-disulfide reductase activity protein disulfide isomerase activity disulfide oxidoreductase activity Cellular component endoplasmic reticulum lumen membrane intracellular membrane-bounded organelle dendrite endoplasmic reticulum endoplasmic reticulum membrane Biological process release of sequestered calcium ion into cytosol 4-hydroxyproline metabolic process extracellular matrix organization protein maturation by protein folding cell redox homeostasis response to endoplasmic reticulum stress chaperone cofactor-dependent protein refolding endoplasmic reticulum unfolded protein response intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress protein folding brown fat cell differentiation cellular response to hypoxia response to temperature stimulus apoptotic process protein folding in endoplasmic reticulum cellular response to oxidative stress Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 30001 50527 Ensembl ENSG00000197930 ENSMUSG00000021831 UniProt Q96HE7 Q8R180 RefSeq (mRNA) NM_014584 NM_015774 RefSeq (protein) NP_055399 NP_001369393 NP_001369394 NP_001369395 NP_001369396 NP_001369397 NP_001369398 NP_001369399 NP_001369400 NP_001369401 NP_001369402 NP_001369403 NP_001369404 NP_001369405 NP_056589 Location (UCSC) Chr 14: 52.64 – 52.7 Mb Chr 14: 45.52 – 45.56 Mb PubMed search [3] [4]
Wikidata
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Interactions

ERO1L has been shown to interact with TXNDC4^[7] and P4HB.^[7][8]