Ets variant 3

Ets variant 3 is a protein that in humans is encoded by the ETV3 gene.^[5]

ETV3
Identifiers
Aliases	ETV3, METS, PE-1, PE1, bA110J1.4, ETS variant 3, ETS variant transcription factor 3
External IDs	OMIM: 164873; MGI: 1350926; HomoloGene: 21085; GeneCards: ETV3; OMA:ETV3 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q23.1 Start 157,121,191 bp[1] End 157,138,474 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F1 Start 87,432,714 bp[2] End 87,447,463 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of arm skin of thigh skin of hip gingival epithelium jejunal mucosa palpebral conjunctiva corpus epididymis cardiac muscle tissue of right atrium tail of epididymis amniotic fluid Top expressed in mesenteric lymph nodes hair follicle skin of back skin of external ear left colon Rostral migratory stream olfactory epithelium subcutaneous adipose tissue left lung lobe cumulus cell More reference expression data BioGPS n/a
Gene ontology Molecular function DNA-binding transcription factor activity DEAD/H-box RNA helicase binding DNA binding sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific molecular function DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component RNA polymerase II transcription repressor complex transcription repressor complex nucleus Biological process regulation of transcription by RNA polymerase II cell differentiation regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II cellular response to granulocyte macrophage colony-stimulating factor stimulus transcription, DNA-templated negative regulation of cell population proliferation biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2117 27049 Ensembl ENSG00000117036 ENSMUSG00000003382 UniProt P41162 Q8R4Z4 RefSeq (mRNA) NM_001145312 NM_005240 NM_001083318 NM_001286844 NM_012051 NM_001359750 RefSeq (protein) NP_001138784 NP_005231 NP_001076787 NP_001273773 NP_036181 NP_001346679 Location (UCSC) Chr 1: 157.12 – 157.14 Mb Chr 3: 87.43 – 87.45 Mb PubMed search [3] [4]
Wikidata
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