Exocyst complex component 6b

Exocyst complex component 6B is a protein that in humans is encoded by the EXOC6B gene.^[5]

EXOC6B
Identifiers
Aliases	EXOC6B, SEC15B, SEC15L2, exocyst complex component 6B, SEMDJL3
External IDs	OMIM: 607880; MGI: 1923164; HomoloGene: 44781; GeneCards: EXOC6B; OMA:EXOC6B - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p13.2 Start 72,175,984 bp[1] End 72,826,041 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 C3 Start 84,595,469 bp[2] End 85,046,495 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon internal globus pallidus corpus callosum sural nerve external globus pallidus pars compacta pars reticulata left ventricle right auricle of heart apex of heart Top expressed in otic vesicle gastrula dentate gyrus of hippocampal formation granule cell primary visual cortex olfactory epithelium superior frontal gyrus central gray substance of midbrain lumbar subsegment of spinal cord hippocampus proper molar More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component exocyst membrane Biological process exocytosis vesicle docking involved in exocytosis protein transport Golgi to plasma membrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23233 75914 Ensembl ENSG00000144036 ENSMUSG00000033769 UniProt Q9Y2D4 A6H5Z3 RefSeq (mRNA) NM_015189 NM_001321729 NM_001321730 NM_001321731 NM_001321733 NM_001321734 NM_177077 RefSeq (protein) NP_001308658 NP_001308659 NP_001308660 NP_001308662 NP_001308663 NP_056004 NP_796051 Location (UCSC) Chr 2: 72.18 – 72.83 Mb Chr 6: 84.6 – 85.05 Mb PubMed search [3] [4]
Wikidata
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Function

In yeast and rat, Sec15 is part of a multiprotein complex that is required for targeted exocytosis.^[5]