Extended synaptotagmin-2

Extended synaptotagmin-2 is a protein that in humans is encoded by the ESYT2 gene.^[5][6]

ESYT2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DMG, 4NPJ, 4NPK, 4P42
Identifiers
Aliases	ESYT2, CHR2SYT, E-Syt2, FAM62B, extended synaptotagmin protein 2, extended synaptotagmin 2
External IDs	OMIM: 616691; MGI: 1261845; HomoloGene: 32699; GeneCards: ESYT2; OMA:ESYT2 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q36.3 Start 158,730,995 bp[1] End 158,830,253 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12 F2|12 62.65 cM Start 116,244,816 bp[2] End 116,354,670 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in synovial membrane Achilles tendon saphenous vein synovial joint endothelial cell urethra cardiac muscle tissue of right atrium myocardium of left ventricle skin of arm skin of hip Top expressed in interventricular septum decidua uterus umbilical cord ascending aorta superior cervical ganglion secondary oocyte cervix granulocyte gastrula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium-dependent phospholipid binding calcium ion binding protein binding metal ion binding phosphatidylinositol binding phosphatidylethanolamine binding phosphatidylcholine binding identical protein binding lipid binding cadherin binding Cellular component intrinsic component of endoplasmic reticulum membrane organelle membrane contact site integral component of membrane extrinsic component of cytoplasmic side of plasma membrane plasma membrane integral component of plasma membrane membrane endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum-plasma membrane contact site Biological process lipid transport endocytosis glycosphingolipid metabolic process transport endoplasmic reticulum-plasma membrane tethering Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57488 52635 Ensembl ENSG00000117868 ENSMUSG00000021171 UniProt A0FGR8 Q3TZZ7 RefSeq (mRNA) NM_020728 NM_028731 RefSeq (protein) NP_065779 NP_001354702 NP_083007 Location (UCSC) Chr 7: 158.73 – 158.83 Mb Chr 12: 116.24 – 116.35 Mb PubMed search [3] [4]
Wikidata
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