F-2 (drug)

F-2, also known as 6-(2-aminopropyl)-5-methoxy-2-methyl-2,3-dihydrobenzofuran or as benzofuran-2-methyl-5-methoxy-6-(2-aminopropane), is a lesser-known psychedelic drug. F-2 was first synthesized by Alexander Shulgin. In his book PiHKAL, the minimum dosage is listed as 15 mg, and its duration is unknown.^[1] F-2 produces few to no effects at this dose in humans. Animal studies showed it to substitute for the psychedelic drug DOM, but with less than one tenth the potency.^[2] F-2 is the derivative of 6-APDB with a methyl group at the carbon atom of the 3,4-methylenedioxy ring and a methoxy group at the 6 position.

F2

Legal status
Legal status	CA: Schedule I UK: Class A
Identifiers
IUPAC name 1-(5-Methoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)propan-2-amine
CAS Number	99355-74-5 Y
PubChem CID	13056773
ChemSpider	21106309 Y
UNII	75S5T5T7QX
ChEMBL	ChEMBL102877 Y
Chemical and physical data
Formula	C13H19NO2
Molar mass	221.300 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=C2C(=CC(=C1CC(C)N)OC)CC(O2)C
InChI InChI=1S/C13H19NO2/c1-8(14)4-10-7-13-11(5-9(2)16-13)6-12(10)15-3/h6-9H,4-5,14H2,1-3H3 Y Key:XBHKBTCXRYPZMX-UHFFFAOYSA-N Y
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Legality

United Kingdom

This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act.^[3]

See also

• F (psychedelic)
• F-22 (drug)
• Substituted benzofuran