FAM177A1

Family with sequence similarity 177 member A1 (FAM177A1) is a protein that in humans is encoded by the FAM177A1 gene, previously known as C14orf24.^[3] The other member of this family is FAM177B.

FAM177A1
Identifiers
Aliases	FAM177A1, C14orf24, family with sequence similarity 177 member A1
External IDs	HomoloGene: 27852; GeneCards: FAM177A1; OMA:FAM177A1 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q13.2 Start 35,044,907 bp[1] End 35,113,130 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon myocardium of left ventricle left testis right testis corpus callosum C1 segment mucosa of transverse colon rectum right lung upper lobe of left lung n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 283635 n/a Ensembl ENSG00000151327 n/a UniProt Q8N128 n/a RefSeq (mRNA) NM_173607 NM_001079519 NM_001289022 n/a RefSeq (protein) NP_001072987 NP_001275951 NP_775878 n/a Location (UCSC) Chr 14: 35.04 – 35.11 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Function

FAM177A1 has been linked to immune system regulation^[4] and to neurogenesis.^[5][6]

Interactions

IntAct reports physical interactions between FAM117A1 and these other human proteins:^[7]

• Aquaporin-6
• Caspase 6
• DPM3
• ELOVL4
• FATE1
• JAGN1
• LAMP2
• PBX3
• SGPL1
• SH3GLB1
• TMX2