FCMR

Fc fragment of IgM receptor is a protein that in humans is encoded by the FCMR gene. ^[5]

FCMR
Identifiers
Aliases	FCMR, TOSO, FAIM3, Fc fragment of IgM receptor, Fc mu receptor, FcmuR
External IDs	OMIM: 606015; MGI: 1916419; HomoloGene: 48347; GeneCards: FCMR; OMA:FCMR - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 206,903,317 bp[1] End 206,923,247 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E4 Start 130,793,406 bp[2] End 130,808,528 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spleen granulocyte lymph node appendix blood epithelium of nasopharynx bone marrow cell thymus mucosa of ileum tonsil Top expressed in mesenteric lymph nodes spleen blood subcutaneous adipose tissue embryo white adipose tissue submandibular gland bone marrow embryo granulocyte More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 9214 69169 Ensembl ENSG00000162894 ENSMUSG00000042474 UniProt O60667 A1KXC4 RefSeq (mRNA) NM_001142472 NM_001142473 NM_001193338 NM_005449 NM_026976 RefSeq (protein) NP_001135945 NP_001180267 NP_005440 NP_081252 NP_001392822 Location (UCSC) Chr 1: 206.9 – 206.92 Mb Chr 1: 130.79 – 130.81 Mb PubMed search [3] [4]
Wikidata
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Function

Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).