FMR1-AS1 gene

In molecular biology, FMR1 antisense RNA 1 (FMR1-AS1), also known as ASFMR1 or FMR4, is a long non-coding RNA. The FMR1-AS1 gene overlaps, and is antisense to, the CGG repeat region of the FMR1 gene.^[3] Its expression is upregulated in fragile X syndrome premutation carriers, and silenced in patients with fragile X syndrome.^[3][4] FMR1-AS1 has an anti-apoptotic function.^[4]

FMR1-AS1
Identifiers
Aliases	FMR1-AS1, ASFMR1, FMR1-AS, FMR1AS, FMR4, FMR1-AS1 gene, FMR1 antisense RNA 1, FMR1 antisense RNA 1 (head to head)
External IDs	OMIM: 300805; GeneCards: FMR1-AS1; OMA:FMR1-AS1 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq27.3 Start 147,909,431 bp[1] End 147,911,817 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence lymph node liver skeletal muscle tissue duodenum prefrontal cortex gallbladder blood olfactory zone of nasal mucosa n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 100126270 n/a Ensembl ENSG00000268066 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr X: 147.91 – 147.91 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

See also

• Long noncoding RNA