FUT1

Galactoside 2-alpha-L-fucosyltransferase 1 is an enzyme that in humans is encoded by the FUT1 gene.^[5]

FUT1
Identifiers
Aliases	FUT1, HH, HSC, fucosyltransferase 1 (H blood group), H
External IDs	OMIM: 211100; MGI: 109375; HomoloGene: 120; GeneCards: FUT1; OMA:FUT1 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.33 Start 48,748,011 bp[1] End 48,755,390 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 B3|7 29.39 cM Start 45,266,713 bp[2] End 45,270,483 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas paraflocculus of cerebellum upper lobe of left lung body of stomach right lung buccal mucosa cell palpebral conjunctiva gingival epithelium middle temporal gyrus apex of heart Top expressed in lip embryo esophagus skin of external ear thymus spermatid skin of back epidermis epiblast jejunum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity galactoside 2-alpha-L-fucosyltransferase activity fucosyltransferase activity glycosyltransferase activity Cellular component integral component of membrane Golgi cisterna membrane Golgi apparatus integral component of plasma membrane membrane Biological process protein glycosylation L-fucose catabolic process fucosylation carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2523 14343 Ensembl ENSG00000174951 ENSMUSG00000008461 UniProt P19526 O09160 RefSeq (mRNA) NM_000148 NM_001329877 NM_001384359 NM_001271981 NM_008051 RefSeq (protein) NP_000139 NP_001316806 NP_001258910 NP_032077 Location (UCSC) Chr 19: 48.75 – 48.76 Mb Chr 7: 45.27 – 45.27 Mb PubMed search [3] [4]
Wikidata
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The enzyme is involved in the synthesis of the H antigen.