FUT9

Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT9 gene.^[5][6][7]

FUT9
Identifiers
Aliases	FUT9, Fuc-TIX, fucosyltransferase 9
External IDs	OMIM: 606865; MGI: 1330859; HomoloGene: 4800; GeneCards: FUT9; OMA:FUT9 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q16.1 Start 96,015,974 bp[1] End 96,215,612 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4 A3|4 10.59 cM Start 25,609,332 bp[2] End 25,800,244 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pylorus cerebellar vermis Brodmann area 46 endothelial cell orbitofrontal cortex postcentral gyrus Brodmann area 23 middle temporal gyrus entorhinal cortex pars reticulata Top expressed in lobe of cerebellum cerebellar vermis lateral geniculate nucleus medial geniculate nucleus dorsal tegmental nucleus medial dorsal nucleus lateral hypothalamus medial vestibular nucleus deep cerebellar nuclei globus pallidus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function glycosyltransferase activity alpha-(1->3)-fucosyltransferase activity fucosyltransferase activity transferase activity Cellular component integral component of membrane Golgi apparatus Golgi cisterna membrane membrane Golgi membrane Biological process L-fucose catabolic process fucosylation nervous system development protein glycosylation carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10690 14348 Ensembl ENSG00000172461 ENSMUSG00000055373 UniProt Q9Y231 O88819 RefSeq (mRNA) NM_006581 NM_010243 RefSeq (protein) NP_006572 NP_034373 Location (UCSC) Chr 6: 96.02 – 96.22 Mb Chr 4: 25.61 – 25.8 Mb PubMed search [3] [4]
Wikidata
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FUT9 is one of several alpha-3-fucosyltransferases that can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. FUT9 synthesizes the LeX oligosaccharide (CD15), which is expressed in organ buds progressing in mesenchyma during human embryogenesis.[supplied by OMIM]^[7]