Fluminorex

Fluminorex is a centrally acting sympathomimetic which is related to other drugs such as aminorex and pemoline. It was developed as an appetite suppressant by McNeil Laboratories in the 1950s.^[1][2]

Fluminorex

Clinical data
ATC code	none
Identifiers
IUPAC name (RS)-5-[4-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-oxazol-2-amine
CAS Number	720-76-3 Y
PubChem CID	24100
ChemSpider	22530 Y
UNII	LUO2Z7954T
KEGG	D04210 Y
ChEMBL	ChEMBL2107247
CompTox Dashboard (EPA)	DTXSID00862387
Chemical and physical data
Formula	C10H9F3N2O
Molar mass	230.190 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES FC(F)(F)c1ccc(cc1)C2O\C(=N/C2)N
InChI InChI=1S/C10H9F3N2O/c11-10(12,13)7-3-1-6(2-4-7)8-5-15-9(14)16-8/h1-4,8H,5H2,(H2,14,15) Y Key:NMGYDYBWRZHLHR-UHFFFAOYSA-N Y
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Synthesis

Synthesis:^[3] Patent (Ex XV):^[4]

2-amino-1-[4-(trifluoromethyl)phenyl]ethanol [776-02-3] (1) cyanogen bromide [506-68-3] (2)

See also

• 4'-Fluoro-4-methylaminorex
• 4-Methylaminorex
• Aminorex
• Clominorex
• Cyclazodone
• Fenozolone
• Pemoline
• Thozalinone