Forkhead box b1

Forkhead box B1 is a protein that in humans is encoded by the FOXB1 gene. ^[5]

FOXB1
Identifiers
Aliases	FOXB1, FKH5, HFKH-5, forkhead box B1
External IDs	OMIM: 619961; MGI: 1927549; HomoloGene: 8138; GeneCards: FOXB1; OMA:FOXB1 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q22.2 Start 60,004,234 bp[1] End 60,061,730 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9 D|9 38.76 cM Start 69,664,992 bp[2] End 69,668,222 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in hypothalamus substantia nigra gonad C1 segment left testis right testis placenta right uterine tube lymph node endometrium Top expressed in tail of embryo neural plate lumbar subsegment of spinal cord embryo mammillary body embryo mesoderm neural groove tibiofemoral joint somite More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding DNA-binding transcription factor activity protein binding sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process visual learning somitogenesis negative regulation of neuron apoptotic process mammillary body development mammillothalamic axonal tract development regulation of transcription, DNA-templated axon target recognition mammary gland lobule development thalamus development transcription, DNA-templated floor plate development telencephalon cell migration cell migration in diencephalon inferior colliculus development spinal cord development urogenital system development lactation midbrain development epithelial cell differentiation involved in mammary gland alveolus development hypothalamus cell migration regulation of transcription by RNA polymerase II anatomical structure morphogenesis cell differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27023 64290 Ensembl ENSG00000171956 ENSMUSG00000059246 UniProt Q99853 Q64732 RefSeq (mRNA) NM_012182 NM_022378 RefSeq (protein) NP_036314 NP_071773 Location (UCSC) Chr 15: 60 – 60.06 Mb Chr 9: 69.66 – 69.67 Mb PubMed search [3] [4]
Wikidata
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