GABA receptor antagonist

GABA receptor antagonists are drugs that inhibit the action of GABA. In general these drugs produce stimulant and convulsant effects, and are mainly used for counteracting overdoses of sedative drugs.

Examples include bicuculline, securinine and metrazol, and the benzodiazepine GABA_A receptor antagonist flumazenil.

Other agents which may have GABA_A receptor antagonism include the antibiotic ciprofloxacin,^[1] tranexamic acid,^[2] thujone,^[3] ginkgo biloba,^[4] and kudzu.^[5]

See also

• GABA_A receptor negative allosteric modulators

External links

• GABA+antagonists at the U.S. National Library of Medicine Medical Subject Headings (MeSH)