GABRR3

Gamma-aminobutyric acid receptor subunit rho-3 is a protein that in humans is encoded by the GABRR3 gene.^[5] The protein encoded by this gene is a subunit of the GABA_A-ρ receptor.

GABRR3
Identifiers
Aliases	GABRR3, gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene), gamma-aminobutyric acid type A receptor subunit rho3 (gene/pseudogene), gamma-aminobutyric acid type A receptor subunit rho3
External IDs	MGI: 3588203; HomoloGene: 26716; GeneCards: GABRR3; OMA:GABRR3 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q11.2 Start 97,985,102 bp[1] End 98,035,315 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C1.3 Start 59,227,695 bp[2] End 59,284,867 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad islet of Langerhans liver right lobe of liver spleen nucleus accumbens Top expressed in primary oocyte secondary oocyte neural layer of retina zygote embryo vasculature vasculature of organ spinal cord temporal lobe amygdala More reference expression data BioGPS n/a
Gene ontology Molecular function chloride channel activity GABA-A receptor activity extracellular ligand-gated ion channel activity ion channel activity transmembrane signaling receptor activity protein domain specific binding Cellular component membrane integral component of membrane cell junction GABA-A receptor complex plasma membrane postsynaptic membrane synapse chloride channel complex cellular component integral component of plasma membrane neuron projection Biological process gamma-aminobutyric acid signaling pathway chloride transport chloride transmembrane transport ion transport chemical synaptic transmission ion transmembrane transport signal transduction regulation of membrane potential nervous system process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 200959 328699 Ensembl ENSG00000183185 ENSMUSG00000074991 UniProt A8MPY1 B2RXA8 RefSeq (mRNA) NM_001105580 NM_001081190 RefSeq (protein) NP_001099050 NP_001074659 Location (UCSC) Chr 3: 97.99 – 98.04 Mb Chr 16: 59.23 – 59.28 Mb PubMed search [3] [4]
Wikidata
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