GALNT13

Polypeptide N-acetylgalactosaminyltransferase 13 is an enzyme that in humans is encoded by the GALNT13 gene.^[5][6][7]

GALNT13
Identifiers
Aliases	GALNT13, GalNAc-T13, polypeptide N-acetylgalactosaminyltransferase 13
External IDs	OMIM: 608369; MGI: 2139447; HomoloGene: 62167; GeneCards: GALNT13; OMA:GALNT13 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q23.3-q24.1 Start 153,871,922 bp[1] End 154,453,979 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 C1.1 Start 54,436,317 bp[2] End 55,118,309 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar cortex cerebellar hemisphere right hemisphere of cerebellum gonad corpus callosum testicle C1 segment Achilles tendon secondary oocyte cerebellar vermis Top expressed in lobe of cerebellum habenula cerebellar vermis dorsal striatum lumbar spinal ganglion olfactory tubercle lateral septal nucleus nucleus accumbens substantia nigra neural layer of retina More reference expression data BioGPS n/a
Gene ontology Molecular function glycosyltransferase activity transferase activity metal ion binding carbohydrate binding polypeptide N-acetylgalactosaminyltransferase activity Cellular component integral component of membrane Golgi membrane Golgi apparatus membrane Biological process protein glycosylation O-glycan processing protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 114805 271786 Ensembl ENSG00000144278 ENSMUSG00000060988 UniProt Q8IUC8 Q8CF93 RefSeq (mRNA) NM_001301627 NM_052917 NM_173030 RefSeq (protein) NP_001288556 NP_443149 NP_001363321 NP_001363323 NP_001363327 NP_001363329 NP_001363330 NP_001363331 NP_001363332 NP_001363333 NP_001363334 NP_766618 Location (UCSC) Chr 2: 153.87 – 154.45 Mb Chr 2: 54.44 – 55.12 Mb PubMed search [3] [4]
Wikidata
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The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM]^[7]