GANAB

Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene.^[5][6][7]

GANAB
Identifiers
Aliases	GANAB, G2AN, GLUII, GIIA, glucosidase II alpha subunit, PKD3
External IDs	OMIM: 104160; MGI: 1097667; HomoloGene: 5426; GeneCards: GANAB; OMA:GANAB - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.3 Start 62,624,826 bp[1] End 62,646,726 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 A Start 8,875,435 bp[2] End 8,894,036 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium islet of Langerhans ventricular zone right ovary left ovary right lobe of thyroid gland body of pancreas canal of the cervix smooth muscle tissue body of uterus Top expressed in cumulus cell ventricular zone yolk sac neural layer of retina gastrula epiblast lip tail of embryo dentate gyrus of hippocampal formation granule cell right kidney More reference expression data BioGPS More reference expression data
Gene ontology Molecular function hydrolase activity, hydrolyzing O-glycosyl compounds catalytic activity hydrolase activity carbohydrate binding hydrolase activity, acting on glycosyl bonds glucan 1,3-alpha-glucosidase activity RNA binding protein binding alpha-glucosidase activity Cellular component melanosome Golgi apparatus endoplasmic reticulum lumen glucosidase II complex membrane extracellular exosome endoplasmic reticulum extracellular matrix intracellular membrane-bounded organelle Biological process metabolism protein folding carbohydrate metabolic process N-glycan processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23193 14376 Ensembl ENSG00000089597 ENSMUSG00000071650 UniProt Q14697 Q8BHN3 RefSeq (mRNA) NM_198335 NM_001278192 NM_001278193 NM_001278194 NM_014610 NM_198334 NM_001329222 NM_001329223 NM_001329224 NM_001329225 NM_001293621 NM_008060 RefSeq (protein) NP_001265121 NP_001265122 NP_001265123 NP_001316151 NP_001316152 NP_001316153 NP_001316154 NP_938148 NP_938149 NP_001280550 NP_032086 Location (UCSC) Chr 11: 62.62 – 62.65 Mb Chr 19: 8.88 – 8.89 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

GANAB has been shown to interact with PTPRC.^[8][9][10]