GINS1

DNA replication complex GINS protein PSF1 is a protein that in humans is encoded by the GINS1 gene.^[5][6][7]

GINS1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2E9X, 2EHO, 2Q9Q
Identifiers
Aliases	GINS1, PSF1, GINS complex subunit 1, IMD55
External IDs	OMIM: 610608; MGI: 1916520; HomoloGene: 44516; GeneCards: GINS1; OMA:GINS1 - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p11.21 Start 25,391,008 bp[1] End 25,452,700 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 G3 Start 150,747,320 bp[2] End 150,773,200 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte sperm embryo ventricular zone right testis left testis ganglionic eminence endothelial cell trabecular bone Top expressed in medial ganglionic eminence primitive streak fetal liver hematopoietic progenitor cell otic vesicle ventricular zone spermatocyte tail of embryo otic placode abdominal wall primary oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function 3'-5' DNA helicase activity Cellular component cytoplasm nucleus nucleoplasm GINS complex Biological process DNA replication DNA strand elongation involved in mitotic DNA replication DNA strand elongation involved in DNA replication inner cell mass cell proliferation DNA duplex unwinding Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9837 69270 Ensembl ENSG00000101003 ENSMUSG00000027454 UniProt Q14691 Q9CZ15 RefSeq (mRNA) NM_021067 NM_001163476 NM_027014 RefSeq (protein) NP_066545 NP_001156948 NP_081290 Location (UCSC) Chr 20: 25.39 – 25.45 Mb Chr 2: 150.75 – 150.77 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• GINS (protein complex)
• Eukaryotic DNA replication#GINS Explains role of GINS during DNA replication in eukaryotic cells.