GLRA2

Glycine receptor subunit alpha-2 is a protein that in humans is encoded by the GLRA2 gene.^[5]

GLRA2
Identifiers
Aliases	GLRA2, GLR, glycine receptor alpha 2, MRXSP
External IDs	OMIM: 305990; MGI: 95748; HomoloGene: 31070; GeneCards: GLRA2; OMA:GLRA2 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xp22.2 Start 14,529,298 bp[1] End 14,731,812 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X F5|X 76.75 cM Start 163,912,013 bp[2] End 164,110,389 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle ganglionic eminence cerebellar hemisphere right hemisphere of cerebellum Hypothalamus prefrontal cortex ventricular zone rectum cingulate gyrus anterior cingulate cortex Top expressed in lumbar subsegment of spinal cord ventral tegmental area lateral hypothalamus lateral septal nucleus anterior amygdaloid area paraventricular nucleus of hypothalamus nucleus of stria terminalis nucleus accumbens substantia nigra dorsomedial hypothalamic nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding glycine binding transmitter-gated ion channel activity chloride channel activity glycine-gated chloride ion channel activity extracellularly glycine-gated chloride channel activity extracellular ligand-gated ion channel activity ion channel activity transmembrane signaling receptor activity transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component synapse integral component of membrane cell projection cell junction integral component of plasma membrane postsynaptic membrane membrane chloride channel complex plasma membrane neuron projection glycinergic synapse Biological process neuropeptide signaling pathway chloride transmembrane transport chloride transport ion transport cellular response to amino acid stimulus synaptic transmission, glycinergic cellular response to ethanol cellular response to zinc ion excitatory postsynaptic potential ion transmembrane transport signal transduction chemical synaptic transmission regulation of membrane potential response to amino acid nervous system process regulation of postsynaptic membrane potential Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2742 237213 Ensembl ENSG00000101958 ENSMUSG00000018589 UniProt P23416 Q7TNC8 RefSeq (mRNA) NM_001118885 NM_001118886 NM_001171942 NM_002063 NM_183427 NM_001357099 NM_001357100 RefSeq (protein) NP_001112357 NP_001112358 NP_001165413 NP_002054 NP_906272 NP_001344028 NP_001344029 Location (UCSC) Chr X: 14.53 – 14.73 Mb Chr X: 163.91 – 164.11 Mb PubMed search [3] [4]
Wikidata
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See also

• Glycine receptor