GLTP

Glycolipid transfer protein is a protein that in humans is encoded by the GLTP gene.^[5][6][7]

GLTP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1SWX, 1SX6, 2EUK, 2EUM, 2EVD, 2EVL, 2EVS, 2EVT, 3RIC, 3RWV, 3RZN, 3S0I, 3S0K, 4GH0, 4GHP, 4GHS, 4GIX, 4GJQ, 4GVT, 4GXD, 4GXG, 4H2Z
Identifiers
Aliases	GLTP, glycolipid transfer protein
External IDs	OMIM: 608949; MGI: 1929253; HomoloGene: 41133; GeneCards: GLTP; OMA:GLTP - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q24.11 Start 109,850,945 bp[1] End 109,880,541 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 F Start 114,807,459 bp[2] End 114,829,045 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of arm gingival epithelium human penis skin of thigh vulva mucosa of pharynx oral cavity skin of hip nasal epithelium mucosa of ileum Top expressed in skin of external ear superior surface of tongue epidermis lip transitional epithelium of urinary bladder hair follicle skin of back esophagus skin of abdomen condyle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding lipid binding glycolipid transfer activity glycolipid binding lipid transfer activity identical protein binding ceramide 1-phosphate binding ceramide 1-phosphate transfer activity Cellular component cytoplasm cytosol membrane Biological process lipid transport glycosphingolipid metabolic process glycolipid transport intermembrane lipid transfer ceramide transport ceramide 1-phosphate transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51228 56356 Ensembl ENSG00000139433 ENSMUSG00000011884 UniProt Q9NZD2 Q9JL62 RefSeq (mRNA) NM_016433 NM_019821 RefSeq (protein) NP_057517 NP_062795 Location (UCSC) Chr 12: 109.85 – 109.88 Mb Chr 5: 114.81 – 114.83 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

The protein encoded by this gene is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. It is thought to be a cytoplasmic protein.^[7]