GNAT3

Guanine nucleotide-binding protein G(t) subunit alpha-3, also known as gustducin alpha-3 chain, is a protein subunit that in humans is encoded by the GNAT3 gene.^[5]

GNAT3
Identifiers
Aliases	GNAT3, GDCA, G protein subunit alpha transducin 3, HG1E
External IDs	OMIM: 139395; MGI: 3588268; HomoloGene: 24284; GeneCards: GNAT3; OMA:GNAT3 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.11 Start 80,458,635 bp[1] End 80,512,064 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 A3 Start 18,167,547 bp[2] End 18,224,832 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad tibialis anterior muscle duodenum abdominal wall mucosa of small intestine prefrontal cortex right lobe of thyroid gland left lobe of thyroid gland large intestine Top expressed in mucosa of large intestine intestinal epithelium tongue epithelium of colon mucosa of small intestine neural layer of retina vallate papilla secondary oocyte epithelium of small intestine white adipose tissue More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity metal ion binding nucleotide binding guanyl nucleotide binding G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity Cellular component acrosomal vesicle cytoplasm axoneme heterotrimeric G-protein complex apical plasma membrane plasma membrane photoreceptor outer segment photoreceptor inner segment protein-containing complex Biological process signal transduction sensory perception of umami taste response to nicotine adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway sensory perception of bitter taste sensory perception of taste sensory perception of sweet taste protein folding detection of chemical stimulus involved in sensory perception of bitter taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 346562 242851 Ensembl ENSG00000214415 ENSMUSG00000028777 UniProt A8MTJ3 Q3V3I2 RefSeq (mRNA) NM_001102386 NM_001081143 RefSeq (protein) NP_001095856 NP_001074612 Location (UCSC) Chr 7: 80.46 – 80.51 Mb Chr 5: 18.17 – 18.22 Mb PubMed search [3] [4]
Wikidata
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Gustducin alpha-3 chain is a subunit of the heterotrimeric G protein gustducin that is responsible for basic taste.