GNG12

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 is a protein that in humans is encoded by the GNG12 gene.^[5][6]

GNG12
Identifiers
Aliases	GNG12, G protein subunit gamma 12, HG3A
External IDs	OMIM: 615405; MGI: 1336171; HomoloGene: 32427; GeneCards: GNG12; OMA:GNG12 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p31.3 Start 67,701,475 bp[1] End 67,833,467 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 C1|6 30.68 cM Start 66,873,381 bp[2] End 66,998,334 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in jejunal mucosa skin of thigh nipple secondary oocyte duodenum skin of hip human penis saphenous vein synovial joint vulva Top expressed in gastrula Ileal epithelium right kidney yolk sac islet of Langerhans uterus jejunum cervix zygote ascending aorta More reference expression data BioGPS More reference expression data
Gene ontology Molecular function phosphate ion binding PDZ domain binding protein binding signal transducer activity GTPase activity G-protein beta-subunit binding Cellular component plasma membrane extracellular exosome membrane actin filament heterotrimeric G-protein complex G-protein beta/gamma-subunit complex Biological process cerebral cortex development G protein-coupled receptor signaling pathway cellular response to glucagon stimulus response to lipopolysaccharide signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55970 14701 Ensembl ENSG00000172380 ENSMUSG00000036402 UniProt Q9UBI6 Q9DAS9 RefSeq (mRNA) NM_018841 NM_001177556 NM_001177557 NM_001177558 NM_001177559 NM_001177560 NM_025278 RefSeq (protein) NP_061329 NP_001171027 NP_001171028 NP_001171029 NP_001171030 NP_001171031 NP_079554 Location (UCSC) Chr 1: 67.7 – 67.83 Mb Chr 6: 66.87 – 67 Mb PubMed search [3] [4]
Wikidata
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