GNPDA1

Glucosamine-6-phosphate isomerase 1 is an enzyme that in humans is encoded by the GNPDA1 gene.^[5][6][7]

GNPDA1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1NE7
Identifiers
Aliases	GNPDA1, GNP1, GNPDA, GNPI, GPI, HLN, glucosamine-6-phosphate deaminase 1
External IDs	OMIM: 601798; MGI: 1347054; HomoloGene: 38054; GeneCards: GNPDA1; OMA:GNPDA1 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q31.3 Start 141,991,749 bp[1] End 142,013,041 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 B3 Start 38,460,588 bp[2] End 38,472,056 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in beta cell kidney tubule ventricular zone right adrenal cortex retinal pigment epithelium renal medulla human kidney jejunal mucosa metanephric glomerulus left adrenal gland Top expressed in yolk sac blastocyst right kidney granulocyte morula tail of embryo proximal tubule neural layer of retina muscle of thigh primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding hydrolase activity glucosamine-6-phosphate deaminase activity identical protein binding Cellular component extracellular exosome cytosol cytoplasm Biological process N-acetylglucosamine metabolic process generation of precursor metabolites and energy single fertilization glucosamine catabolic process carbohydrate metabolic process N-acetylglucosamine catabolic process UDP-N-acetylglucosamine biosynthetic process N-acetylneuraminate catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10007 26384 Ensembl ENSG00000113552 ENSMUSG00000052102 UniProt P46926 O88958 RefSeq (mRNA) NM_005471 NM_011937 RefSeq (protein) NP_005462 NP_036067 Location (UCSC) Chr 5: 141.99 – 142.01 Mb Chr 18: 38.46 – 38.47 Mb PubMed search [3] [4]
Wikidata
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