GOLGA3

Golgin subfamily A member 3 is a protein that in humans is encoded by the GOLGA3 gene.^[5][6][7]

GOLGA3
Identifiers
Aliases	GOLGA3, GCP170, MEA-2, golgin A3, Golgin 160
External IDs	OMIM: 602581; MGI: 96958; HomoloGene: 4308; GeneCards: GOLGA3; OMA:GOLGA3 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q24.33 Start 132,768,914 bp[1] End 132,829,078 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 F|5 53.36 cM Start 110,324,567 bp[2] End 110,374,336 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tendon of biceps brachii tibia thymus internal globus pallidus cardia stromal cell of endometrium saphenous vein oocyte dorsal motor nucleus of vagus nerve pylorus Top expressed in ankle muscle of thigh right ventricle seminiferous tubule molar calvaria medullary collecting duct atrioventricular valve myocardium of ventricle soleus muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding transporter activity cadherin binding Cellular component cytoplasm Golgi transport complex Golgi cisterna membrane cytosol Golgi membrane Golgi apparatus nucleolus membrane nucleus nucleoplasm extrinsic component of Golgi membrane Biological process intra-Golgi vesicle-mediated transport spermatogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2802 269682 Ensembl ENSG00000090615 ENSMUSG00000029502 UniProt Q08378 P55937 RefSeq (mRNA) NM_001172557 NM_005895 NM_008146 NM_001347389 RefSeq (protein) NP_001166028 NP_005886 NP_001334318 NP_032172 Location (UCSC) Chr 12: 132.77 – 132.83 Mb Chr 5: 110.32 – 110.37 Mb PubMed search [3] [4]
Wikidata
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The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis.

This gene encodes a member of the golgin family of proteins which are localized to the Golgi. Its encoded protein has been postulated to play a role in nuclear transport and Golgi apparatus localization. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined.^[7]